Cryo-electron microscopy (Cryo-TEM or Cryo-EM) is the next evolution step of Electron Microscopy:

• unaltered by drying in vacuum imaging, unlike conventional TEM

• fast specimen freeze coverts water into transparent ice crystals

• ice crystal transforms biomolecules in a rigid state allowing high-resolution imaging

• sub 10 Å resolution (1 nm) allows imaging near-atomic structures

• quick-fire imaging allows using a high power beam of 200 kV.