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Cryo-electron microscopy (Cryo-TEM or Cryo-EM) is the next evolution step of Electron Microscopy:
unaltered by drying in vacuum imaging, unlike conventional TEM
fast specimen freeze coverts water into transparent ice crystals
ice crystal transforms biomolecules in a rigid state allowing high-resolution imaging
sub 10 Å resolution (1 nm) allows imaging near-atomic structures
quick-fire imaging allows using a high power beam of 200 kV.
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