High Content Analysis (HCA), also known as High Content Screening (HCS), image cytometry,
quantitative cell analysis or automated cell analysis, is an automated method that is used to
identify substances that alter the phenotype of a cell in a desired manner. This technology is
primarily used in biological research and drug discovery and combines fluorescent microscopy,
automated cell calculations and phenotyping using image-processing algorithms and informatics
tools for the user to make decisions.
Using a combination of established technologies, HCA can address both cellular level intensity
and morphological measurements. With sufficient resolution for subcellular detection, automated
detection and phenotyping can be achieved with intact, fixed or live cells. The table above
describes some common cell-based assays used in laboratories.
HCS Studio Cell Analysis Software
Thermo Scientific™ HCS Studio™ Cell Analysis Software is the engine behind Thermo Scientific
High Content Products. Modeled after common scientific and business applications, HCS Studio
Cell Analysis Software packages our industry favorite software into a simple user interface.
The popular Thermo Scientific™ HCS Studio™ Scan Application and Thermo Scientific™
HCS Studio™ View Applications are located in a central launchpad—Thermo Scientific™ HCS
Studio™ HCS Navigator Application—easily located and docked on your desktop. Featuring 30+
one-click assays, HCS Studio Cell Analysis Software ideally provides smart defaults to get you
closer to the answers you need quickly.