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Mass Spectrometry

LC-MS/MS analysis by Q Exactive, Thermo

Mass Spectrometry

Superior Quantitation

- Advanced quadrupole technology (AQT) improves precursor selection and transmission for more-accurate quantitation of low-abundance analytes in complex matrices
- Sophisticated data-independent acquisition (DIA) and parallel reaction monitoring (PRM) deliver reproducible quantitation with complete qualitative confidence
- An advanced active beam guide (AABG) reduces noise and extends maintenance intervals

Enhanced Analysis of Intact Proteins

- Optional intact protein mode provides superior trapping of large molecules for improved analysis of intact proteins and protein complexes
- Optional enhanced resolution ensures maximum ID confidence in top-down proteomics and lipidomics

High-Confidence Results

- HR/AM and full-scan capabilities capture all sample data, all of the time, enabling retrospective data analysis without need to re-run samples
- Resolving power up to 140,000 FWHM eliminates isobaric interferences, increasing confidence in results when analyzing samples in complex matrices
- Better than 1-ppm mass accuracy in full- and all-ion fragmentation (AIF) scan modes ensures confident compound identification
- Fast scanning at 12 Hz and spectral multiplexing suited to UHPLC applications
- Rapid polarity switching maximizes information obtained
- AIF and multiple dissociation techniques — in-source CID and HCD — aid in compound identification
- Mass range to 6000 m/z enhances detection of singly charged small molecules and biomolecules
- More than four orders of magnitude intrascan dynamic range, along with femtogram-level sensitivity, allow detection of trace-level and high-abundance compounds in the same scan

For Research Use Only. Not for use in diagnostic procedures.

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