Quatt Zetaview by Particle Metrix

NTA

Zetaview is a versatile and robust instrument based on NTA technique, allowing visualization and quantification on critical particles parameters.
Key details:
- analysis of particles in suspension, 1 mL of test solution required
- particles concentration range 1E+7 to 1E+9
- particles size range: 10 nm to 1000 nm for metals, 50 nm to 1000 nm for organic particles
- Each particle is independently measured
- Zeta-potential range -100 to +100 mV
- detection of all particles and independently sub-population of fluorescent particles in any of 4 channels:
A. ex 405nm/ em 410nm B. ex 488nm/ em 500nm C. ex 520nm/ em 550nm D. ex 640nm/ em 660nm
- Co-localization of fluorescent labels on particles

Multi-color fluorescent NTA

While NTA technique is most commonly used to profile EVs and nanoparticles size, size distribution, and concentration, the fNTA enables a whole new field of research applications:

- fluorescent membrane labeling allows to assess EVs samples purity and sort out membranous vesicles out of the total number of particles in solution
- biomarkers profiling via fluorescently labeled antibodies is a powerful tool to measure up to 4 different biomarker expression on the same sample, which saves you time and precious material
- RNA/DNA labeling for a perspective class of novel nano-formulations inspired by Moderna’s mRNA vaccine
- drug loading efficiency to validate the number of cargo-carrying particles
- drug release kinetics of the fluorescently labeled drug out of nanoparticles

The fNTA technique combines the abilities of NTA, flow cytometry, and fluorescent microscopy with the advantage of nano-scale real-time analysis.